(Senior) Associate Scientist, Bioanalysis and Immunogenicity

Job description

(Senior) Associate Scientist, Bioanalysis and Immunogenicity

About the opportunity

Bioanalysis and Immunogenicity department is seeking a (Senior) Associate Scientist to help deliver novel medicines to patients across a broad range of drug development stages. In this role you will be completing bioanalytical and immunogenicity studies such as method development, method validation and sample analysis for non-clinical and clinical studies. You will be working in regulated (GLP/GcLP) and non-regulated environments, so a high level of quality needs to be maintained.

About Ablynx

Ablynx, a Sanofi company, is a biopharmaceutical company dedicated to creating new antibody-based medicines called Nanobodies® which are making a real difference to society. Ablynx currently has over 400 people working on the development of Nanobodies for the treatment of a wide range of diseases, including inflammation, immuno-oncology and rare diseases.

The Bioanalysis and Immunogenicity department develops ligand-binding assays for pharmacokinetic (PK), immunogenicity (ADA) and biomarker (BM) analyses.

About growing with us

The successful applicant will be executing laboratory experiments, analyse data and report results to evaluate novel drug candidates in biological samples from clinical and non-clinical studies. Working in a regulated environment (GLP/GcLP), means an understanding of GLP principles, will be an advantage. Experience with electronic laboratory tools such as LIMS and electronic notebooks are also a plus.

In this role you will have:

- Active contribution to regulated (GLP/GcLP) and non-regulated bioanalytical analyses using Ligand-Binding Assays (LBA, e.g. ELISA, MSD, Gyrolab, …)

·  Develop, optimize and qualify pharmacokinetic, immunogenicity and pharmacodynamic assays to analyze the pharmacokinetic, immunogenic and pharmacodynamic properties of Nanobodies® and other biologic macromolecules
·  Execute method validation and troubleshooting, if needed
·  Sample testing in support of PK and immunogenicity analysis using LIMS (ThermoFisher Watson)
·  Accurate documenting and reporting of experimental procedures and results
·  Analyzing data and preparing written results reports in English
·  Communicating results and observations to the supervisor and team in English

- Technical responsibility for other related laboratory duties as required (e.g. instrument and system maintenance and documentation)

About you

The position requires excellent laboratory skills, critical thinking, and attention to detail at the bench and the desk. The position is primarily a laboratory position. Accuracy in documentation (compiling/review of data tables and reports/ instrument maintenance and documentation) will also be required.

Qualifications/Education & Work experience

·  Degree B. Sc., M. Sc. Biotechnology/(Bio)chemistry/Pharmacology/Industrial engineer or equivalent preferably with 1-2 years of relevant experience. More experienced candidates are encouraged to apply. Entry level will depend upon level of experience
·  Proven general lab skills, including experience with the set-up and optimization of ELISA-based immunoassay techniques
·  Solid analytical and problem-solving skills, including data analysis and mathematical skills
·  Quality-oriented - prior experience in a regulated (bio)analytical laboratory (GLP, GcLP or possibly GMP) is a plus

Competencies

·  Excellent self-organization, time management and documentation skills
·  Strong communication (verbal, written, interpersonal, listening) skills
·  Ability to work independently with minimal supervision
·  Ability to adapt to rapidly changing priorities
·  Ability to multi-task and meet timelines in a fast-paced environment
·  Team player
·  Excellent English skills (oral and written)
·  Knowledge of MS Office (Excel, Word, PowerPoint) required; knowledge of Watson LIMS, SAS JMP and/or Prism GraphPad is a plus
·  Available for full time position

The CV of the applicant needs to be in English and should include a paragraph specifying the technical expertise.

A temporary contract (12 months) will be offered, with a possibility to extend or convert into a permanent contract.

Inspire your Journey, what Sanofi can offer you

·  An international work environment, in which you can develop your talent and realize ideas and innovations within a competent team
·  An individual and well-structured introduction and training when you onboard
·  You can create your own career path within Sanofi. Your professional and personal development will be supported purposefully
·  As a globally successful and constantly growing company, Sanofi provides international career paths as well

This is our Sanofi, Discover yours.

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.