Senior Scientist, Computational Biologist - AIDD

Job description

The Position

As a member of the AI, Data and Digital (AIDD) team, you will partner with research scientists and data experts at China Innovation Center of Roche (CICoR) on drug projects from target identification to lead discovery and early development. You have strong biology knowledge and computational skills in combination with an excellent capacity to communicate and lead in a multi-disciplinary environment. You will employ a combination of analytical capability including bioinformatics/AI skills and disease biology knowledge to provide timely bioinformatics studies to impact decision makings in drug projects.
- Partner with AI researchers and bioinformaticians to develop novel computational methods to infer causality in disease progression.
- Work closely with biologists in Immunology and Oncology to solve biological questions and validate computational findings.
- Contribute to drug projects by providing support on target identification and validation, biomarker discovery, patient stratification, clinical trial design, etc.
- Analyze multi-omics and phenotyping data from research studies, clinical trials and real world databases to identify disease-driving cell types, pathways, and genes.
- Propose drug targets based on the biology insights derived from data and suggest validation experiments.
- Provide literature/text analysis, focusing on biomedical and competitor information.
- Have the opportunities to collaborate with data scientists and informaticians at other Roche sites to contribute to drug projects as well as data & analytics projects.
- Have the opportunity to lead data science/AI initiatives and projects.

Who you are
You’re someone who wants to drive your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company’s global culture.

• - Ph.D. degree in bioinformatics, biology, computational biology or a relevant field. Experience in the pharmaceutical industry is preferred. 
• 5+ years of industry experience, or 3+ years in industry plus 2+ years academic post-doc experience
• - Passion for in-depth understanding of biological questions and finding plausible answers with data analytics.
• - Solid biology knowledge in Immunology or Oncology, being able to communicate comfortably with biologists.
• - Excellent analytical capability, being able to identify key questions and come up with innovative solutions for complex problems.
• - Strong bioinformatics experience (omics, pathway, network analysis, etc.) with good programming skills in Python or R. 
• - Experience with biomarker discovery and translation is a plus.
• - Experience with clinical or real world data is a plus.
• - Experience with text mining or competitor information analysis is a plus.
• - Enjoying biotech working culture with great collaborative spirit.
• - A strong team player with good communication skills in both English and Mandarin.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an Equal Opportunity Employer.