Scientist, Systems Biology, I2O DTA, pRED

Job description

·  Job facts

At Roche, over 90,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives and we are fearless in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The Position

The Immunology, Infectious diseases and Ophthalmology (I2O) Disease Therapeutic Area (DTA) of Roche Pharmaceutical Research and Early Development (pRED) strives to discover and develop new drugs for autoimmune, inflammatory, infectious, and eye diseases with unmet medical need.

The I2O Systems Biology group, located in Basel, is an integral component of the I2O drug discovery and early development pipeline, supporting data generation and knowledge management across the DTA, deepening disease understanding and proposing new drug targets and biomarkers based on systematic, unbiased, data-driven approaches.

In this role, you will assimilate into a team of systems biologists, responding and adapting to results-oriented project goals in an agile manner. The capacity to form close collaborative relationships with biologists and clinicians within the I2O DTA, and technical teams in other functions, is essential. In return, the work environment will be highly dynamic and rewarding.

Projects will include, but will not be limited to, one or more of the following activities:

·  deepening disease understanding in areas of unmet medical need;
·  delivering innovative and sustainable sources of targets for entry into portfolio;
·  facilitating the development of biomarkers for early drug development;
·  ensuring the reverse translation of clinical studies into target discovery;

Who we are

At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Desired profile

Who You Are

You're someone who wants to influence your own development. You are looking for a company where you receive the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

In addition, you have the following qualifications and experience:

·  You hold a Ph.D. or an M.D. in a biomedical (e.g. Immunology, Microbiology, Ophthalmology, Medicine, Veterinary Sciences), computational (e.g. Computer Science, Physics, Mathematics, Statistics) or interdisciplinary field (e.g. Systems Biology, Computational Biology, Bioinformatics, Biomedical Engineering, Biostatistics)
·  You have 3-5 years' postdoctoral research experience in academia or industry, with a strong record of publication and/or patents;
·  You have experience identifying targets and biomarkers using unbiased, data-driven approaches;
·  You have a deep expertise in data science, exemplified by one or more of the following:
·  You have experience working with and integrating multiple different types of orthogonal datasets;
·  You have experience utilizing and developing algorithms for mining complex biomedical data, including statistics and machine learning;
·  You are familiar with data & knowledge management practices and have a good understanding of knowledge graphs;
·  You are able to translate biomedical questions into actionable analytical plans (algorithms, software etc.) and communicating them to technical experts;
·  You are able to translate complex, heterogeneous data into biologically interpretable models of disease and communicating them effectively to biologists and clinicians;
·  You have strong scripting and programming skills, preferably in R and/or Python;
·  You are comfortable managing and interacting with multiple stakeholders within and outside the department and contributing to several projects in parallel;
·  You are enthusiastic about learning new concepts and technologies and you easily show engagement with your peers and supervisors;
·  You are fluent in English.

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients' lives. If you want to work in a passionate team, make your mark and improve lives, apply now.

Applications need to include a motivation letter, a CV and contact details of 3 referees. The preferred start date of this position is as soon as possible – please clearly indicate your preferred starting date in your motivation letter.

Roche embraces diversity. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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