Research Associate (50%)

Job description

·  Job facts

Who We Are

At Roche, over 90,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other's differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

The Roche Innovation Center Zurich is active in the research and development of engineered therapeutic antibodies, with a focus on the fields of cancer immunotherapy and immunotherapy in general. Part of the Roche Group since 2005, it employs about 180 people.

The Position

As a Research Associate (50%) you will join the CIT-2 Department at Roche Innovation Center Zürich (Schlieren, Switzerland) and interact closely with a team of scientists working on novel classes of cancer immunotherapy agents. You will focus on performing in vitro and ex vivo biological assays to characterize the activity of new molecules and understand their mode-of-action.

The principal responsibilities will include:

·  Planning, conducting, analyzing and interpreting in vitro/ex vivo assays based on tumor/immune cell (co-)cultures
·  Assessment of antibody binding, antibody-mediated tumor cell killing, immune cell phenotyping, assessment of immune cell activation, proliferation, cytokine secretion and downstream signalling events
·  Maintenance of in vitro cell cultures and routine quality controls of molecules and batches
·  Laboratory manager responsibilities including daily lab routine, ordering supplies, monitoring inventory and contracts will also be required
·  Data analysis and interpretation, contribution to preparation of scientific presentations and writing of scientific reports
·  Presentation of generated data packages in project team meetings
·  Co-ordination of material supply, exchange and alignment of protocols and data interpretation with external collaborations
·  Accurate documentation of assays and close collaboration with team members to allow efficient job-sharing

The position is permanent and part-time (50%) and the start date would be February 1st, 2020 or shortly thereafter.

Who we are

Das Roche Innovation Center Zürich (Roche Glycart AG) ist in der Erforschung und Entwicklung gentechnischer therapeutischer Antikörper tätig. Schwerpunkte sind die Krebs-Immuntherapie sowie die Immuntherapie allgemein. Glycart gehört seit 2005 zur Roche-Gruppe und beschäftigt zirka 140 Mitarbeitende. Mehr dazu .

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.

Desired profile

Who You Are

You're someone who wants to influence your own development and is looking for continuous learning and development. You're looking for a company where you have the opportunity to pursue your interests across functions and geographies, and where a job title is not considered the final definition of who you are, but the starting point.

For this position you bring the following qualifications:

·  Bachelor, Master's degree or Lab technician with comprehensive research experience in cell biology or tumor immunology (no PhD)
·  Excellent hands-on experience with mammalian cell culture, Isolation and handling of immune cells from blood (human, mouse, cyno)
·  Excellent experience with tumor cell-immune cell cultures and co-cultures, various cell biology techniques and state-of-the art immunoprofiling techniques for functional characterization of immune cell responses (e.g. multiparametric analysis by flow cytometry, CBA or multiplexing, MACS sorting, ELISA, luminescence, live cell imaging by Incucyte)
·  Good written and verbal English is mandatory
·  Strong communication and presentation skills
·  Ability to work effectively and independently within a diverse group of people
·  Excellent organizational skills, ability to take initiative and work with a high degree of flexibility to timelines
·  Close collaboration with team members required

* For non-EU / EFTA citizens: Please state your eligibility status to work in Switzerland (e.g. B-Permit, C-Permit) and note that if you do not own a valid Swiss work permit, Roche cannot guarantee your final employment due to authority regulations.

** PhD's and Postdocs''s cannot be considered for associate roles in Roche pRED. ​

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients' lives. If you want to work in a passionate team, make your mark & improve lives, apply now.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

If you have questions, please check our FAQs and videos on careers.roche.ch/faq.

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