Principal Scientist I

Job description

·  Job facts

The Principal Scientist I will be part of the Diagnostic PCR Assay development team in Pleasanton within the Roche Sequence Solutions business, .focusing on the optimization and early development of oncology assays and applications for use on next-generation sequencing platforms. We are looking for a motivated and team-oriented individual who is passionate about finding new ways to win the war on cancer by revolutionizing cancer diagnosis. The successful candidate will design, lead and execute advanced independent and diagnostic studies to support the early development of assays and to assess interesting clinical questions, defining study goals and analysis plans and applying advanced scientific knowledge to complete projects

Essential Functions:

·  Designs, optimizes, and provides technical expertise related to multiplexed PCR assays.
·  Assists with conceiving, planning, and conducting advanced independent experiments from project inception through the product lifecycle.
·  Contribute to assessing new technologies that have potential to meet current and future diagnostics needs.
·  Analyzes data, evaluates results, forms conclusions, and determines future experiments.
·  Nucleic acid extraction from clinical samples including tissue and blood.
·  Applies advanced technical writing skills to prepare written summaries, internal reports, presentations, manuscripts, etc.
·  Presents findings or comprehensive project status reviews at internal or external seminars/meetings.
·  Interfaces with other departments to align and further project goals
·  Accurately and consistently records experimental methods, materials and results in electronic laboratory notebooks.

Minimum Qualifications:

·  Ph.D. in Biological/Life Sciences or related field; or B.S./Master's degree with 7 or more years of relevant experience.
·  Experience with biological assay design and use of multiplex real-time PCR technologies.
·  Familiarity with Next Generation Sequencing methods.
·  Familiarity with JMP, MS Office, PowerPoint, and ability to learn new technical software rapidly.
·  Must be organized, work accurately, and be comfortable in a fast-paced project.
·  Ability to act independently.
·  Assay development experience is highly preferred. Familiar with quality assurance systems and in vitro diagnostic regulations such as CE-IVD, CLIA, and FDA US-IVD is a plus.
·  Team oriented with excellent interpersonal skills and ability to take ownership and accountability of assignment.
·  Excellent written and oral communication skills and ability to effectively communicate with cross-functional teams.

·  Who we are

At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.