PostDoc in directed evolution of production cell lines at Roche Innovation Center Munich (m/f/d)

Job description

  Job facts

Who we are and what we do:

Large molecule research (LMR) is a world leading technological unit within Roche Pharma Research and Early Development (pRED). LMR generates new therapeutic antibodies according to a specific target compound profile, optimizes the identified lead series and develops a suited clinical lead candidate up to phase I trials.

Our dedication is to deliver highly differentiated biologics that bring game changing benefit to our patients.

In this environment we are looking for a highly motivated Postdoc (m/f/d) in the field of cell biology, molecular biology and directed evolution to enrich our team.

We are offering a unique opportunity to work in a positive, highly dynamic and multidisciplinary environment. You will be working alongside highly skilled fermentation experts, automation specialists, data scientists and researchers in focused teams and apply cutting-edge technologies to solve the most challenging questions in cell culture research.

If this sound attractive to you, please be invited to share your knowledge with us and to expand your skills in one of the world's largest healthcare companies.

This could be your department:

The advertised position is located in the “Cell Culture Research” department in pRED. The main focus of our team is to develop the production process for new therapeutic molecules using CHO cells.

We are a multidisciplinary team that applies world-leading methods in bioprocess engineering, automation, data processing, modeling and machine learning. The department consists of 35 people with diverse qualifications such as engineers in biotechnology, automation specialists and data scientists. We are proud of our team spirit and our hunger for science. We are constantly learning from each other and from others to stay at the forefront of research.

This could be your job:

You will work on the interface between cell line development and upstream process development. The focus of your PostDoc-project is the optimization of production cell lines by using directed evolution approaches.

Among other responsibilities, you can expect the following exciting tasks:

·  Your key responsibilities comprise the development of methods for the directed evolution of CHO production cell lines
·  You will work as a cell biology researcher (m/f/d) within Roche Pharma Research, planning and executing directed evolution experiments in the lab
·  It will be your responsibility to closely interact with scientists from cell line development and upstream process development
·  Presentation of data internally and externally as well as literature search is part of your regular tasks

The publication of results also belongs to your tasks and will be supported.

And what is about you?

·  In any case you are a goal oriented personality, willing to perform wet-lab experiments and you are eager to establish new techniques. Your personal drive is the key value for us.
·  Furthermore, you are well known for your extraordinary team spirit and your willingness to work in international teams
·  You have finished your Master's degree in molecular cell biology or biotechnology or a related field and possessed a PhD degree in this field with at least 3 years research experience
·  We can rely on your strong background in cell biology and molecular biology. Experience in directed evolution would be beneficial.
·  Excellent English skills (written and spoken) complete your profile

This position is limited to a period of two years (with positive results an extension is envisioned) .

We look forward receiving your application!

Whom to contact

E. Hallermayer-Jahreiß +498856/60 19253

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Should you have recruiting specific questions on your application or the specific job posting, please contact the responsible recruiter (E. Hallermayer-Jahreiß, +498856/60 19253).

Application documents

For your application, please keep it simple. We only ask you for an updated CV (in German or English) and for your certificates. All further documents will be handled at a later stage.

·  Who we are

Die Roche Diagnostics GmbH (RDG) ist mit mehr als 12.000 Mitarbeitern der drittgrößte Standort im Konzern. Neben den Vertriebsorganisationen in Deutschland (Roche Pharma AG und Roche Diagnostics Deutschland) fokussiert die RDG auf das operative Geschäft. In den beiden Standorten Mannheim und Penzberg werden neue diagnostische Tests und pharmazeutische Wirkstoffe für den weltweiten Markt entwickelt und produziert.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.