Master Student Internship (12 months), Roche Cell and Organoid Biorepository, Roche Institute of Human Biology (IHB)
Stage Basel, SWITZERLAND IT development
Job description
The Position
In Roche’s Pharmaceutical Research and Early Development organization (pRED) , we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
You will join Roche’s Institute of Human Biology (IHB), an organization within pRED whose goal is to harness and advance the use of human model systems in drug discovery and development, as well as personalized medicine. Our interdisciplinary research bridges academic and pharmaceutical research, connecting biologists, engineers, and data scientists.
We partner and collaborate with leading scientific institutions worldwide to tackle grand challenges by assembling, funding, and leading interdisciplinary teams of experts to work on highly ambitious and complex scientific questions.
Job mission
We are offering an outstanding opportunity for a student researcher to contribute to our mission to disrupt the traditional drug discovery process by advancing more predictive human model systems. Your work in Adipose Tissue Modeling will play a pivotal role in addressing the escalating challenge of metabolic disorders linked to obesity.
This position focuses on developing a cutting-edge adipose organoid model using advanced 3D cell culture technologies and human adult stem cells, to mimic the complex functions of white adipose tissue. Your core mission involves establishing a model that accurately reflects mature adipocyte phenotype including lipid dynamics and gene expression, and assessing its physiological relevance against native tissue benchmarks.
Additionally, you will optimize organoid cryopreservation to ensure model longevity and functionality. This work is critical for propelling our understanding of adipose biology and opening new avenues for metabolic disease treatment.
We seek a driven, detail-oriented student researcher ready to contribute to a transformative project with far-reaching health implications. If you are passionate about pioneering research and eager to make a tangible impact in the field of metabolic health, join us in this exciting venture.
Your impact
Enhances the drug discovery process by developing more predictive human model systems.
Utilizes state-of-the-art 3D cell culture technologies and stem cells to create advanced adipose organoid models.
Aims to replicate the intricate functions of white adipose tissue in vitro, and to improve the study of fat biology.
Compares organoid models to native tissue to ensure physiological accuracy and relevance.
Offers the potential to significantly impact public health by informing the development of novel therapeutics for metabolic conditions.
Your profile
As a Master's student conducting your thesis research in our lab, you will thrive in an environment that encourages autonomy and values your unique contributions to our collaborative projects. Your adaptability and creativity in problem-solving will be key as you navigate the challenges of your research. We expect you to work well within our team, embracing an inclusive approach that leverages diverse perspectives. Your dedication to cultivating a supportive atmosphere, engaging in knowledge exchange, and pursuing continuous learning will be crucial for the success of your thesis and the advancement of our collective scientific goals.
You have experience in tissue modeling, preferably adipose tissue. Prior work with 3D cell culture technologies and stem cell research is highly desirable.
You have a B.Sc. degree in Biology, Bioengineering, or a related field with a focus on cellular and molecular biology.
You have strong analytical and problem-solving skills to address complex scientific questions and challenges in the field of metabolic disease research.
You show meticulous attention to detail to ensure the accuracy and quality of research outputs.
You have scientific curiosity, as well as effective communication and documentation skills in English.
You are self-motivated and driven to contribute to transformative projects with the potential for significant health implications.
You have the ability to work effectively in a collaborative environment, contributing to a team's success while advancing independent research goals.
Our commitment
Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees in their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
General requirements
You must be an enrolled university student in a Master's program
Due to regulations: Non-EU/EFTA citizens are required to submit a document (Mandatory Letter) from their university stating that an internship is mandatory as part of the application documents. Additionally, Non-EU/EFTA citizens must remain continuously enrolled in their university program for the entire duration of the internship
We look forward to receiving your application documents, which should include an updated resume, a cover letter, and a current enrollment certificate.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.