Interdisciplinary Student Internship in Bioinformatics and Chemoinformatics

Job description

  Job facts

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives. We are brave in both decision and action, we believe that good business means a better world.

The internship will focus on collecting safety-relevant data of small molecules from high-throughput screening results and integrating them with other types of data including compound-target binding information and gene expression to identify driving factors underlying safety liabilities of drug candidates. As an intern operating on a cross-department research project, you will work in close collaboration with scientists in Roche Pharma Research and Early Development (pRED) using and developing state-of-the-art bioinformatics and chemoinformatic tools and resources. The knowledge and knowhow can potentially benefit future drug discovery programs by reducing costs and increasing success rate of preclinical safety evaluation.

During your internship your tasks will include:

·  Evaluate, collect, and curate relevant data
·  Exploratory statistical analysis and visualisations of the data
·  Integration of multiple data sources
·  Assessment of safety risk factors by statistical modelling including machine learning
·  Interpret and report the results with the assistance of experts in different fields

Your profile

We are keen to discover talents who are passionate about learning and show great curiosity in discovering new things. At the Roche Headquarter site in Basel/Kaiseraugst, employees from over 90 countries are doing now what our patients need next. We contribute our share towards achieving our mission and to make our vision of personalized healthcare happen. We offer you a multicultural workplace in a modern environment, which at the same time requires you to be open-minded and adaptable. This also means that you continuously contrast your results with others and acknowledge the benefit of teamwork and communications. You will be a member of the Roche Interns Network that offers you chances to connect, have fun and get to know Basel, in the heart of Europe.

You are a dynamic enrolled master/Ph.D. Student in Bioinformatics, Cheminformatics or a related field with a strong interest in interdisciplinary research and drug discovery. You work diligently and independently, are motivated by the possibility of performing state of the art research with different types of data, and are passionate about working on a problem with practical impacts.

Furthermore, you have/are:

·  Proficiency in working with bioinformatics or chemoinformatics tools and methods
·  Good knowledge of R, Python, C/C++, Pipeline Pilot/KNIME, or other programming languages with proven records of good programming and documentation styles
·  Good communication skills in English
·  Teamwork and collaboration skills
·  Knowledge in biological sciences, medicinal chemistry, and drug discovery is a plus
·  enjoying to work with big data volume

Information about application documents and start date:

The preferred start date of the internship is July 2018 or upon availability.

Applications need to include a CV and a cover letter, as well as two References.

Due to regulations non-EU/EFTA citizens have to provide a certificate from the university stating that an internship is mandatory as part of the application documents. Please note that non-EU/EFTA nationals have to successfully apply for a Swiss work permit.

Tags: ROiQQ ROiLS ROiBI ROiEE ROiCE ROiTEC ROiDIGROiCHI​​

·  Who we are

At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.