BS/MS Biochemistry/Enzymology Research Associate Oncology - SANDOZ - Cambridge - Wizbii

BS/MS Biochemistry/Enzymology Research Associate Oncology

  • By SANDOZ
  • Cambridge (United Kingdom)
2018-09-20T00:42:20+0000

Job description

Job Description

The Biological Chemistry (BC) group is an early stage drug discovery team within Oncology research at NIBR, focused on understanding and exploiting the molecular mechanisms of novel cancer targets for the discovery, characterization and optimization of small molecule therapeutics. We are seeking a highly motivated, creative and collaborative scientist to join our team in a hands-on role to discover the next generation of innovative cancer treatments.

Responsibilities for the role include:
•Functional and mechanistic characterization of enzymes, substrates, and multi-protein complexes.
•Design, development, and troubleshooting of diverse biochemical and biophysical assays for use in the assessment of both mechanism and small molecule modulation of cancer targets, including hit identification, validation, and optimization.
•Analysis, interpretation, documentation, and presentation of data to the BC group and multidisciplinary project teams.
•Assessment of emerging technologies with an emphasis towards the implementation of new experimental techniques enabling drug discovery.
•Contribution to group organization, productivity, and expertise through collaboration and idea exchange.
Posting Title

BS/MS Biochemistry/Enzymology Research Associate Oncology

Seeked profile

Minimum requirements

•BA/BS or MS degree in Biophysics, Biochemistry, Enzymology or a related field with some relevant laboratory experience through employment, internships, or coursework.
•An understanding of protein function, protein-ligand binding interactions, and enzyme mechanisms.
•Experience with biochemical and/or biophysical assay development for protein target and small molecule inhibitor characterizations is preferred.
•Familiarity with fluorescence-based assay techniques (e.g. HTRF, FP, DSF) and label-free technologies (e.g. SPR, ITC, LC-MS) is desired.
•An interest in implementing innovative assay technologies and developing novel assay approaches to support drug discovery programs.
•Hands-on experience with automation to enable medium throughput assays is a plus.
•Demonstrated ability to analyze, interpret, and present data in a clear manner.
•An excellent team-player with strong communication and inter-personal skills.
At NIBR we believe that along with our scientists, our culture is our greatest asset. To drive that culture each employee is expected to function in an innovative and collaborative manner. Each successful candidate will be able to demonstrate how they have functioned in this manner to drive results.
Job Type

Full Time
Country

USA
Work Location

Cambridge, MA
Functional Area

Research & Development
Division

NIBR
Business Unit

Oncology NIBR
Employment Type

Regular
Company/Legal Entity

NIBRI
EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

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About SANDOZ

Sandoz, une division de Novartis, est un leader mondial parmi les fabricants de médicaments génériques. Sandoz (26400 collaborateurs répartis parmi 130 pays avec un CA de 9.6 milliards USD en 2014) met à disposition des patients et des professionnels de santé des médicaments de qualité dont les prix maitrisés facilitent l’accès aux soins et contribuent à l’optimisation des dépenses de santé. Sandoz France fonde son développement sur la confiance des patients, de ses clients, de ses partenaires et appuie son succès sur : une recherche permanente de l’innovation, tant pour ses produits (génériques et biosimilaires) que pour ses actions ; Un portefeuille large, qui inclut une offre croissante de biosimilaires et qui répond aux besoins essentiels de santé publique ; Le savoir-faire industriel du Groupe Novartis, et de plus de 40 partenaires français ; L’engagement d’équipes fières et responsables, réunies autour d’une vision commune et de valeurs partagées.

1091 vacancies open at SANDOZ

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