Senior Scientist – Analytical Chemistry

Job description

Job Description

About Chemical & Analytical Development, work in a Chemical Development Unit:
The Chemical & Analytical Development (CHAD) serves the interests of Novartis through timely supply of synthetic active pharmaceutical ingredients for clinical and development needs, with responsible process and analytical R&D leading to successful regulatory approval, launch and commercialization. CHAD associates develop and utilize appropriate methodologies to manufacture and analyze bulk pharma chemicals in a safe, efficient, cost-effective, environmentally responsible, under GMP and through application of expertise in chemistry, engineering and Technical Life Cycle Management.
One of three Chemical Development Units based on the Basel Campus is looking for an independent and motivated, master degree-level educated scientist with proven experience in analytical method development (e.g. HPLC, GC, titration, LC-MS) to join the Analytical Team.

Description and Key Responsibilities:
You will be responsible for the development, optimization and validation of robust analytical methods for the quantification and identification of by- and degradation products in raw materials, intermediates and active pharmaceutical ingredients.
You will be responsible for the release of synthetic intermediates according to current SOPs & GMP guidelines for timely manufacturing of clinical supplies.
You will be responsible for the setting up of stability programs in GLIMS, evaluation of shelf life, contribution to specification setting of raw materials & intermediates.
You will be responsible for the process transfer to Chemical Operations for launch campaigns.
Write, review & approve analytical GMP documents (e.g. analytical methods, validation reports, raw data, qualification reports for analytical instruments, etc.) for upload into Novartis databases.
In addition you will operate and maintain chromatography devices coupled with non-UV detection systems (e.g. MS, CAD, ELSD) and will be responsible for setup and maintenance of the assigned laboratory infrastructure and equipment.
You will work closely with analytical and process development chemists as well as scientists from a diverse range of disciplines within Chemical and Analytical Development to contribute to the overall analytical project strategy. Other requirements include a strong technical-scientific background, good understanding of GMP, excellent communication skills and the ability to work independently in a team environment.

Desired profile

A MS degree from University (eventually a “FH-diploma” would be considered) in chemistry or chemistry related field.
Preferably 2-5 years experience in the pharmaceutical industry, a plus in analytical development.
Candidate must have strong scientific knowledge within analytical chemistry & method development and a sound understanding of organic chemistry, along with the interest in growing scientifically.
Additionally the candidate must have the ability to multitask, support several parallel projects, and communicate with analytical chemists and scientists at all stages of the project.
Fluent in English (oral and in writing), German may be of advantage.
Desirable: GMP knowledge (work history in cGMP environment).