in vivo and Molecular Biology Research Associate

Job description

Job Description

The Chemical Biology & Therapeutics (CBT) department is looking for a highly motivated Associate skilled in research with animals and molecular biology/cell biology. CBT is involved in multiple stages and therapeutic areas of the drug discovery process with a goal of validating targets implicated in diseases caused by pathway deregulation, and testing/progressing drug candidates that modulate these pathways.
The successful candidate will be responsible for:
- Conducting in vivo and ex vivo experiments on animal models of diseases, including colony maintenance of genetic disease models, development and induction of disease models (surgically or chemically-induced), delivery of candidate drug regimens, making clinical observations, and harvesting samples for the evaluation of drug levels, histology, and molecular endpoints.
- Development, implementation and characterization of new animal models in rodents and possibly pigs.
- Execution of standard molecular biology and cell biology techniques in order to support evaluations of pharmacodynamics (i.e. cell, tissue or explant culture, Western blot analyses, ELISAs, quantitative PCR, etc).
- Independent planning, execution, documentation, analysis and interpretation of experiments.
- Presentation of results in both written and oral format and delivery of completed reports within a multidisciplinary team environment.
- Contributing to the general lab infrastructure, including ordering of consumables and coordinating with other associates about the workflow, organization, maintenance, and function of lab resources.
- Establishing and maintaining excellent working relationships with critical collaborative partners throughout the company.

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

Desired profile

Minimum requirements

• BS, MS or PhD degree in a biological or chemical science discipline or Professional training as a laboratory technician.
• At least 3 years of post-graduate research experience in either an industry or academic laboratory setting.
• Direct, hands-on experience in the conduct of rodent in vivo pharmacology experiments.
• Fluency and excellent communication skills in English.
• Strong organizational skills, self-motivation, attention to detail, flexibility, proactive willingness and desire to engage in the laboratory workflow, and an ability to contribute to a multidisciplinary team environment are essential.
• The applicant should have a strong practical background in molecular biology, cell biology, and biochemical techniques.
• Experience and proficiency with animal models to evaluate regenerative medicine is strongly preferred. Prior experience in cell biology and/or molecular biology techniques is preferred. Experience in working with pig pharmacology models is preferred.