Scientific Director, Anatomic Pathologist

Job description

Janssen Research & Development, LLC ., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientific Director located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.janssenrnd.com/ for more information.

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

Janssen Pharmaceutical Company, a member of the Johnson & Johnson Family of Companies, is recruiting an experienced Veterinary Anatomic Pathologist, at the Scientific Director level to join the Tox/Path/LAM Team within the nonclinical Safety group. The successful candidate will work locally with global collaboration to deliver scientific support to Drug Discovery, Development Projects and Investigative Problem-solving Teams.
As a Scientific Director, Pathologist, responsibilities will include but not limited to the following:
Study Pathologist/Compound Pathologist:
· Function as a study pathologist on safety assessment, discovery and pharmacology studies to include review of experimental/research protocols, provision of gross and microscopic evaluation of tissues and reporting of integrated results on a variety of nonclinical studies aimed at improving pre-clinical to clinical translation of both safety and efficacy.
· Review Pathology reports and provide scientific input in determining hazard identification, risk assessment and risk management within the framework of nonclinical Safety, while providing guidance that influences the development and implementation of mitigation strategies that will facilitate successful NME declaration.
· Ensure consistent on time delivery, to Study Directors, of high quality Pathology data and Pathology reports for all Preclinical Toxicology studies to meet project goals and milestones.
· Utilize a broad knowledge of pathophysiology across veterinary species to provide scientific leadership in collaboration with the functional representative (PCDL) on Discovery/Development and/or cross sector research project teams.
· Provide Pathology support for in-licensing activities for the therapeutic area.
· Collaborate with stakeholders at all levels to optimize processes within Pathology to maximize efficiency and drive project progression; demonstrate and introduce innovation in both local and global components of the drug discovery and/or development process.

· Develop, review, approve, implement and refine proposed strategies that support studies conducted by members of the pathology section in support of discovery projects; drive project progression through innovative scientific and technical leadership; guide hypothesis-driven pathology investigations that evaluate efficacy models, target-related toxicities, and mode of action of toxicity issues.
· Develop and/or implement tools of molecular (IHC, TMA, ISH and fluid-based biomarkers), clinical, and anatomic pathology integrated with other molecular biology tools (e.g toxicogenomics) for utilization in discovery support and/or mode of action investigative toxicology studies. These tools include but are not limited to in situ hybridization, immunohistochemistry, quantitative image analysis, ligand binding assays, hematology, clinical chemistry, urinalysis, etc.
· Provide leadership, scientific direction and guidance to the identification and development of novel biomarkers of target organ toxicity
Discovery Toxicologist Role
· Serve as a Pre-clinical team representative for some early Discovery Projects to provide advice on translational and safety issues to Discovery Scientists within Janssen R&D; regarding scientific strategies and technical competencies required/available within Pathology and Toxicology discipline for efficient issue resolution to deliver projects successfully.

Desired profile

Qualifications :

·  DVM (equivalent) AND PhD (will consider someone that will be receiving PhD by September 2018) with at least 3 years of anatomic pathology experience is required
·  Board certified by American/European College of Veterinary Pathologists (ACVP or ECVP) is required
·  Excellent written, communication skills and recognized knowledge and expertise in the field of anatomic pathology is required
·  A solid scientific publication record is required
·  Current working knowledge and experience in the field of pre-clinical GLP toxicological pathology/anatomic pathology is preferred
·  Experience and/or training in immunology/immunopathology is preferred