Associate Scientist, Protein Expression

Job description

Job Description

Requisition ID: 4096190116

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for an Associate Scientist, Protein Expression to be in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visithttp://www.janssenrnd.com/ for more information.

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it. Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

The new Lead Discovery team is a critical part of the Discovery Sciences organization in Janssen R&D and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area discovery teams. This mission requires deep scientific expertise in several disciplines including chemistry, cellular pharmacology, screening and protein science coupled with an ability to work collaboratively with internal and external partners.

The Protein Science department within Lead Discovery is responsible for the delivery of proteins to enable assay development, HTS, pharmacological profiling and structural biology (X-ray crystallography and NMR). The Protein Science Team collaborates closely with Janssen Therapeutic Areas and functional teams and with external collaborators in academia and industry. We seek individuals with a strong ability to connect key stake holders for the delivery of goals and objectives, fostering an environment of collaboration, collegiality and positive communication, and who show superior performance in the context of a multidisciplinary, geographically disperse team. The Associate Scientist, Protein Expression will:

·  Contribute to protein expression design strategies to produce biologically active proteins for use in assays and structural biology.
·  Participate in protein expression activities including expression optimization & screening from bench-scale to scale-up utilizing bacterial ( E. coli ), insect (BEVS), and mammalian expression systems.
·  Assist the evaluation and implementation of new protein expression approaches and technologies to improve capabilities and workflows.
·  Analyze, interpret, summarize and report experimental data
·  Stay current with scientific literature and apply relevant learnings to the design and interpretation of protein expression experiments.
·  Exhibit a high level of productivity and promote effective team-working in the laboratory.
·  Collaborate in a fast-paced, results-driven environment across multiple therapeutic and functional disciplines in the US, Europe and Asia.
·  Attend in-house seminars and external scientific meetings as appropriate

Desired profile

Qualifications

·  A minimum Bachelor's degree in biology, chemistry, or related discipline, an Advanced degree is preferred.
·  A minimum 2 or more years of relevant lab-based research experience is preferred.
·  Prior experience in recombinant protein production is required.
·  Expertise in protein expression analysis using techniques such as electrophoresis and Western Blot is required.
·  Expertise in the production of complex recombinant proteins in multiple expression systems including E. coli , insect /or mammalian cell lines is preferred.
·  Experience with flow cytometry , FSEC, protein pull-downs is preferred.
·  Experience working with automated laboratory workflows and instrumentation is preferred.
·  Expertise in protein construct design is preferred.
·  The position will be based at the J&J site in Springhouse, PA.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location
United States-Pennsylvania-Spring House-1400�McKean�Road
Organization
Janssen Research & Development, LLC. (6084)
Job Function
R&D
Requisition ID
4096190116