Scientist, Cell Based Assay Development Job

Job description

Scientist, Cell Based Assay Development-6393150508DescriptionJanssen Research & Development, L.L.C., a member of Johnson & Johnson's Family of Companies is recruiting for an Scientist, in Biologics Research to be located in Springhouse, PA.Janssen Biotech, Inc. delivers on the promise of new treatments and ways to improve the health of individuals with serious disease. Built upon a legacy of innovative firsts, Janssen Biotech pursues advancing patient care with immunology and oncology solutions. Please visit http://www.janssenbiotech.com/ for more information.
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The Biologics Research Assay Group at Janssen Research and Development is seeking a Scientist. The Assay Group develops and qualifies assays to evaluate biopharmaceutical candidates and their targets. The incumbent will work within the Department to initiate and support discovery programs in collaboration with partners in Janssen. The successful candidate will likely be involved in multiple programs in multiple therapeutic areas.
The primary responsibility for this position will be to develop and qualify biochemical and cell-based assays for hit discovery, lead optimization, and lead characterization of novel candidate therapeutics, contributing to large molecule characterization; structure function analysis and pharmacological mechanism of action studies. The Scientist will design, develop and implement various in vitro assays including binding, signaling, ADCC, ADCP, CDC, T cell activation and cytokine release and enzymatic activity. The successful candidate will also be expected to make significant technical and strategic contributions to research and discovery programs and will be well organized, able to handle large data sets, and distill and communicate results to therapeutic teams. This position requires a strong ability to develop innovative approaches, and a high degree of interaction with collaborators. Experimental work is an important part of the role and the successful candidate will spend a significant part of his/her time at the bench and demonstrate rigorous data documentation and analysis skills. Additional responsibilities include assay trouble shooting and development of new technology platforms.
QualificationsPhD in biochemistry, cell biology or related field is required5 years or less of related experience and/or training or equivalent is preferredMust be a skilled bench scientist with a strong analytical biochemistry background and demonstrated skills in assay developmentExperience with development of protein therapeutics is preferredInterpersonal skills with the ability to interact effectively with people, internally and externally is requiredExperience with cell based functional assays, tissue culture of immortalized and primary cells, and multi-parametric flow cytometry are required; PBMC isolation, transfection techniques, and protein-protein interaction measurements (ELISA, Western Blotting, Meso Scale Discovery (MSD) technology) are preferredFamiliarity in assay automation, liquid handling, immunofluorescence and immunocytochemistry are preferredThe successful candidate will demonstrate clear and professional verbal and written communication, well organized, able to manage multiple projects simultaneously, and meet strict deadlinesBE VITAL in your career, Be seen for the talent you bring to your work. Explore opportunities within the Johnson & Johnson Family of Companies.
J2W:BIOPrimary Location:North America-United States-Pennsylvania-Spring HouseOrganization: Janssen Research & Development, LLC. (6084)Job Function: R&DCertain sites within the Johnson & Johnson Family of Companies participate in E-Verify as appropriate in accordance with Company guidelines and federal or state law. To learn more about the government sponsored program and to see a list of the sites that are currently enrolled, please click here.
Johnson and Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law. EEO is the Law EEO is the Law GINA Supplement