Investigator, Human Genetics

Job description

Your Responsibilities :
We are seeking a motivated, innovative, skilled and enthusiastic geneticist to join our expanding team within the Human Genetics department. Candidates should be keen to apply state of the art genetic knowledge to drive decision making across the GSK pipeline, working in partnership with scientists in HG and in the broader Research organisation, to generate biological insights that will translate into innovative new medicines for patients.

At the core of GSK's R&D approach is the identification of new medicines by leveraging the vast amounts of human genetic and genomic data now being generated and applying cutting edge technologies in functional genomics and machine learning.

Within the Human Genetics team, we leverage major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms and integration of biological pathway and functional genomics data to identify novel targets. We continue to evaluate these targets throughout their life in the pipeline, using genetics and genomics to identify the patients that are most likely to benefit and biomarkers to select these patients and assess efficacy.

The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance GSK drug discovery and clinical development. This field-leading research addresses important drug discovery and development challenges, directly impacts GSK's R&D pipeline, and leads to publication in top scientific journals.

Key Responsibilities include, but are not limited to:
• Identifying and implement opportunities for genetics based science to improve GSK target quality and use human genetic evidence to drive decisions on target selection, validation and patient stratification.
• Be responsible for detailed genetic assessments to inform GSK decisions regarding the projects to start and progress.
• Participating in project teams with GSK scientists and external collaborators. Be responsible for effective communication of genetic findings, with expert interpretation, to relevant stakeholders and project teams.
• Finding creative solutions and work with agility to address challenging scientific questions.
• Contributing to the developing science of drug target identification and validation, providing scientific expertise within Human Genetics and across the Research organization.

Closing Date for Applications: 2nd August COB

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

*LI-GSK
GSKGenetics

Why You?

Basic qualifications:
• M.A., M.S., Ph.D, or equivalent experience in human genetics, statistical genetics, pharmacogenetics, genomics, clinical pharmacology, biology or related field.
• Experience in population based genetic studies, for example GWAS or PheWAS.
• Demonstrated skills working in teams to find creative ways to address scientific questions.
• Strong verbal and written communication skills

Preferred qualifications:
• Data science skills to collect, integrate, mine and analyze complex biological data and translate them into testable hypotheses.
• Knowledge of functional genomics, immunology or epidemiology
• Experience leveraging external collaborations to augment internal capabilities.
• Integration of of additional molecular data, eg from gene expression profiling, metabolomics, or proteomics, into genetic analyses.

Why GSK? :
GlaxoSmithKline is a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. We discover, make and market life-enhancing products that are used by millions of people around the world, helping them to do more, feel better and live longer. We have 3 primary areas of business in pharmaceuticals, vaccines and consumer healthcare. We have offices in more than 115 countries, major research centers in the UK, USA, Spain, Belgium and China and an extensive manufacturing network with 87 sites globally. Our three strategic priorities are to grow a diversified global business, deliver products of value, and to simplify our operating model.

Contact information:
You may apply for this position online by selecting the Apply now button.

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