The position is available in the HSV group led by Professor Marc Labetoulle, for characterisation of newly identified immune responses involved in restricting reactivation of latent HSV1 reservoirs, to be exploited for protective and therapeutic interventions. HSV1 will infect almost all humans at some time in their life, to establish a persistent latent state in sensitive neurons of the trigeminal ganglia. Stress induces reactivation of lytic replication, with diseases caused at peripheral sites by lytic inflammatory viral replication episodes. These include painful cold sores, potentially blinding ocular herpetic keratitis, and HSV1 is implicated in Alzheimer’s disease. The candidate will use advanced molecular and immunology approaches, to further define functional aspects of these immune signatures that are essential for eliciting immunity to reactivation.

Qualification requirements and skills
We seek a hardworking, highly motivated and enthusiastic candidate with:
- A recently acquired PhD in immunology, virology, or a similar field
- A strong background in cellular and molecular biology
- Strong understanding of immunology
- Proficiency in professional English
- Competent computer skills
- High level report writing and oral presentational skills

Experience required
- Immunology methodologies
- tissue culture
- flow cytometry
- experimentation in vivo
- working in ≥ BSL 2 containment

Interested applicants should submit a complete CV, a brief description of their research achievements interests and motivations, and name and contact details for three referees to Professor Marc Labetoulle: mlabetoulle@15-20.fr

Applications close 16 March 2025