Offers “Roche”

Expires soon Roche

Principal Associate

  • Shanghai, CHINA
  • Chemistry / Biology / Agronomy

Job description



·  Job facts

Primary Purpose of Job
Provide purification services to support pRED China project portfolio. Assist medicinal chemists and process chemists to deliver compounds by required timeline.
Be able to communicate effectively in English orally and in written form. Presents and interprets information and issues clearly and concisely to chemists or in discussions. Actively contributes to scientific discussions at team meetings that help to establish a novel method and solve difficulties in compound separation.
Be familiar with Waters AutoP purification system /Gilson Prep HPLC/Shimazu Prep HPLC or Prep SFC. Be able to do simple instrument troubleshooting.
Is current with all required safety training. Follow Roche laboratory safety practices.

Principle Roles & Responsibilities / Accountabilities

1 Provide purification service:

Develop preparative methods, and purify compounds for medicinal chemists and process chemists; communicate well with sponsors to ensure purity, recovery rate and delivery time of desired compounds.
Master Mass-Directed Purification System, including hardware & software installation, configuration; learning handling specific compounds; updating instruments & methods to improve work efficiency.
Familiar with and utilize all the instruments available in purification group.
2 Instruments maintenance and troubleshooting:
Responsible for the maintenance and troubleshooting of all the instruments;
Contact with engineers to repair the instruments.
Modify instrument to implement new technology or improve productivity if necessary
3 Manage Consumables & solvents :
Order & keep the solvent storage and consumable at proper level, no impact on work due to lack of solvents.
4 Team work
Contribute to the development and improvement of preparative HPLC and chiral separation methods;
Exchange purification knowledge with team member and learn from each other.

Qualification and Experience

Education/Qualifications

a)Master degree in analytical chemistry or related field with at least 5-year working experience and 3+year hands experience in compound purification. or
b)Bachelor degree with at least 8-year working experience and 3+year hands experience in compound purification.

Job Required Competencies

Prep HPLC experience is a must.
Rich skills and knowledge in purification or chiral separation.
Be proactive and with passion, self-driven, highly motivated, good team worker and always be eager to learn.
Fluent in reading, written and oral English.

·  Who we are

At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Make every future a success.
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