Offers “Roche”

Expires soon Roche

Lab Associate in neurobiology (radiotracer development & molecular imaging)

  • Internship
  • Basel, SWITZERLAND

Job description



·  Job facts

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives and we are daring in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

This role is within the Biomarkers and Translational Technologies section, which sits within Neuroscience and Rare Diseases (NRD) in Pharma Research & Early Development (pRED). The mission of our team is the development of innovative biomarker strategies for our therapeutic areas particularly focusing on target engagement, mechanism of action, pharmacodynamic response, and identification of responsive patient populations. Our vision is to utilize the most advanced methods including imaging (PET and MRI), EEG, and digital biomarkers to support scientific decision making in early drug development.

The Position

We are looking for a Lab Associate in the field of radiotracer development and positron emission tomography (PET). The Translational PET Lab is located within the Biomarkers and Translational Technologies section and focuses on the development of novel radiopharmaceuticals for brain targets. We characterize tritiated candidate radiotracers in vitro and in vivo using various radiopharmacological, histological and biochemical techniques.

Your key responsibilities are:

·  Cryostat tissue sectioning
·  In vitro and ex vivo autoradiographical experiments
·  Establishment and validation of in vitro radioligand binding assays
·  In vivo experiments with radioactive tracer candidates in rodents
·  Immunohistofluorescence analysis of tissue sections and application of other morphological techniques
·  Image analysis and data processing

We are looking for these skills and qualifications:

·  With a background in biology, you bring experience in pharmacological and morphological techniques and are familiar with the handling of radioactive compounds.
·  Your expertise in tissue sectioning (cryostat) is recommended to be successful in this role.
·  The ideal candidate should possess a basic knowledge in neuropharmacology and neuroanatomy.
·  Prior experience in handling rodents (e.g. injections) is a clear asset to set yourself for success.
·  Familiarity with regulations regarding the handling of radioactivity, animals, restricted substances and chemicals is desired.
·  Fluency in English and/or Germanis a requirement for this role.
·  Good knowledge of data and image analysis software (e.g. Excel, Prism, ImageJ or similar, electronic lab book) is a strong plus.
·  Excellent organizational and communication skills, sense of responsibility, accuracy and urgency and the ability to adjust to new challenges are required for this position.

Are you ready to apply? We are looking for a person who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

For non-EU / EFTA citizens: Please state your eligibility status to work in Switzerland (e.g. B-Permit, C-Permit) and note that if you do not own a valid Swiss work permit, Roche cannot guarantee your final employment due to authority regulations.

PhDs and postdocs graduated cannot be considered for associate roles in Roche pRED.

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq.

Roche is an equal opportunity employer.

·  Who we are

At Roche, 98,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Make every future a success.
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