Intern - Research Biology - Small Molecule Pharmaceutical Sciences - Analytical and Pharmaceutical Chemistry - Master's and PhD Students

Job description

  Job facts

To develop a world-class CMC organization recognized for high quality science, innovative approaches, and ability to rapidly respond to changes in clinical development. To expeditiously develop and deliver phase appropriate formulations, chemical synthesis, process characterizations and controls to enable a robust dynamic and diverse pipeline using innovation high quality science, technologies and partnerships.

Project 1:

This research program is to apply process analytical tools (PAT) to study reaction kinetics and understand reaction mechanism. Target intern is graduate student major in Chemistry with a spectroscopy background. Experiences with reactIR, reactRaman are preferred, but not required. Selected candidate would first learn how to use PAT tools. Next , experiments would be conducted on synthetic reactions using both reactIR and reactRaman. The intern would then spend some time performing PCR and PLS in the instrument software, building calibration curves and conducting multivariate model to determine the quantitative results and reaction kinetics of the reaction.

Project 2:
Chromatography - Perform/operate/carry out a series of experiments using HPLC-MS
ESI-Mass spectrometry - manipulate electrospray ionization techniques to study PEG molecules
Mechanistic Understanding of Chemistry - using chemistry concepts, study mechanism of experiments at hand.

Project 3:
This research program is to apply process analytical tools (PAT) to study reaction kinetics and understand reaction mechanism.Target intern is graduate student major in Chemistry with a spectroscopy background. Experiences with ReactIR, ReactRaman are preferred, but not required. Selected candidate would first learn how to use PAT tools. Next, experiments would be conducted on synthetic reactions using both reactIR and reactRaman. The intern would then spend some time performing PCR and PLS in the instrument software, building calibration curves and conducting multivariate model to determine the quantitative results and reaction kinetics of the reaction.

Target Start Date: Summer 2017

·  Who we are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

Desired profile

Who you are

In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that employees are critical to our success in bringing novel medicines to patients, we are dedicated to remaining a great place to work and to providing employees with programs, services and benefits that allow them to bring the best to the business and to their personal lives.

To be successful in this role, you will be or you will have:

Project 1:

Major in Chemistry, with spectroscopy background

Project 2:
Chemistry - Analytical/Separations Science/Mass Spectrometry

Project 3:
Chemistry, Spectroscopy
·