Protein Mass Spectrometry Bioanalyst

Job description

Your Responsibilities :
We have a new position available at our Global Research and Development campus in Ware. We are seeking a motivated scientist with experience in bioanalysis of biopharmaceutical (e.g. proteins, peptides dAbs, mAbs, ADCs, bi-specifics) using Liquid Chromatography/ Mass Spectrometry.

You will provide deep lab bench level technical knowledge and experience of bioanalysis by applying a wide breadth of sample preparation, separation and detection techniques to develop and validate novel and complex bioanalytical methods.

You will measure drug and metabolites levels in relevant biophases (systemic or at target) to drive pre-clinical and clinical safety and efficacy outcomes. You will be accountable for further development of top down and bottom up proteomics techniques, 2D-HPLC and automation.

Part of the challenge of this role is to establish bioanalytical capability to support, critical quality attributes across our large molecule portfolio, measure circulating immune complexes and further our experience of high-resolution mass spectrometry.
The successful candidate will independently develop, troubleshoot and validate immunoassay methods to support either PK and biomarker endpoints in non-clinical or clinical studies.

Key Responsibilities include, but are not limited to:
• Demonstrate deep knowledge and strong experience in bioanalytical related technologies and their practical application in delivering novel and challenging assays. Acts as an analytical scientific expert in discussions on science/project progression within GSK
• Holds him/herself accountable for delivering high quality bioanalytical assay and results and be fully compliant with regulatory requirements.
• Provide scientific leadership and set strategic direction on technology advancement. Drive an assay technology agnostic attitude and openness to new technologies to support all modalities
• Constantly look for new ways to enhance the value of bioanalytical science that bioanalysis group brings to the group and to support the increasingly diversified GSK portfolio
• Drive innovation, and enable the introduction & investigation of innovative technology. Partner with external companies, institutes and consortium to deliver solutions
• Well-connected in the analytical community (internally and externally to GSK); established through publications and presentations

CLOSING DATE for applications: Monday 12th August (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.
*LI-GSK

Why You?

Basic qualifications:
• PhD or equivalent skills in Chemistry, Biochemistry or related discipline.
• Strong laboratory hands-on experience and theoretical understanding of protein mass spectrometry structure determination or quantification.
• Strong laboratory hands on experience of proteomics workflows complementary to Mass Spectrometry detection (high resolution MS and tandem quadrupole MS)
• Track record of bioanalytical innovation such as implementing new analytical technologies, automation.
• Excellent attention to detail, communication and documentation skills will be expected.

Preferred qualifications:
• Maintains a disciplined approach, ensuring a relentless focus on quality, compliance, scientific rigor and operational excellence.
• Highly motivated team player with a proactive attitude, excellent organizational skills and a demonstrated ability to interact effectively within a multi-disciplinary team are essential.

Why GSK? :
GlaxoSmithKline is a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. We discover, make and market life-enhancing products that are used by millions of people around the world, helping them to do more, feel better and live longer. We have 3 primary areas of business in pharmaceuticals, vaccines and consumer healthcare. We have offices in more than 115 countries, major research centers in the UK, USA, Spain, Belgium and China and an extensive manufacturing network with 87 sites globally. Our three strategic priorities are to grow a diversified global business, deliver products of value, and to simplify our operating model.

Contact information:
You may apply for this position online by selecting the Apply now button.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

jobDetails